Osteoarthritis supplement helps mice live longer

An over-the-counter addition designed to palliate osteoarthritis enlarged a lifespan of lab mice by scarcely a tenth, scientists pronounced Tuesday. This would interpret into an normal eight-year longevity advantage if a outcome could be steady in humans, Swiss researchers reported in a biography Nature Communications.

A group led by Michael Ristow during a Swiss Federal Institute of Technology (ETH) in Zurich used a common dietary addition called glucosamine on laboratory mice after contrast it on worms. Glucosamine is a naturally occurring devalue found in a lubricating liquid that surrounds joints. It is widely sole over a opposite as a addition to fight osteoarthritis, a commonest form of arthritis, nonetheless studies into a efficiency have thrown adult churned results. Ristow’s group initial tested a little sip on a well-researched lab animal, a nematode worm called Caenorhabditis elegans, and found it extended a lifespan by some 5 percent. (Read: Which dishes are abounding in iron and calcium?)

They afterwards experimented with 146 mice only underneath dual years aged — a severe homogeneous of 65 years in tellurian terms. Mice given glucosamine lived on normal 10 percent longer than counterparts who did not get a supplement, that in tellurian terms is about 8 years. Additional work in lab dishes suggested glucosamine had a vast outcome on a metabolic system, a scientists said. It prevents a relapse of vast sugarine molecules into smaller ones, so replicating a ‘low-carb’ diet that restricts intake of carbohydrates. Further work is indispensable to explain because this appears to impact a mice’s longevity — and to see either a advantage extends to humans. (Read: Diet low in nutrients could indeed extend your lifespan!)

‘If an even medium outcome on ageing were proven, it would be a vital advance,’ Tim Spector, a genetic epidemiologist during King’s College London, pronounced in an eccentric comment. ‘However, humans are not a same as worms or rodents, and studies will need clever riposte before we get over-excited.’ (Read: 10 reasons because a Mediterranean diet is good for your health)

 Source: AFP

Image source: AFP

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Osteoarthritis supplement helps mice live longer